GLG News Analyses of the following article:
Breaching a Barrier to Fight Brain Cancer
Published at: www.nytimes.com
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Crossing the Blood Brain Barrier to Fight Glioma Tumors
November 26, 2009
Gliomas are malignant tumor in the human brain. Despite extensive research, prognosis for these patients is poor. One challenge/barrier that prevent chemotherapy agents from entering the brain is the "blood brain barrier." This barrier can be temporarily disrupted to allow passage of chemotherapy agents to enter the brain to fight the tumor. Microcatheters can be used during angiographic procedures to deliver chemotherapy. Avastin, manufactured by Genentech (DNA), is the drug being studied.
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