GLG News Analyses of the following article:

Interim Data From A Clinical Trial Evaluating GI Dynamics' EndoBarrier™ Gastrointestinal Liner In Patients With Type 2 Diabetes

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Published at: www.medicalnewstoday.com

Effective Obesity Treatment with a Removable Medical Device

December 1, 2009

GLG Expert Contributor

Promising new medical strategy, in clinical trials, with intriguing worldwide application, but especially in Western markets.

William HaynesDirector of Clinical PharmacologyTHE UNIVERSITY OF IOWA 
          What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

EndoBarrier has Potential for Treatment of Obesity and Type 2 Diabetes Mellitus

November 30, 2009

Endoscopic placement of the EndoBarrier reduces weight by 14% and HBA1c by 1.5% after 24 weeks. While not reaching the magnitude of weight loss from bariatric surgery, these changes are impressive and substantially exceed those seen with pharmacologic monotherapy. If this efficacy is validated in future trials, and there are no safety issues, this approach could be useful for a large number of obese patients.

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