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A welcome improvement

December 9, 2008

Analysis of:Wyeth Submits European Marketing Authorization Application for its 13-Valent Vaccine for the Prevention of Pneumococcal Disease in Infants and Young Children | phx.corporate-ir.net

With the introduction of Prevnar, there has been a dramatic decline in invasive pneumococcaal disease in young children that has had a herd immunity effect on all ages. There has been a bit of a compensatory increase in serotype 19A disease (not in the current formulation of Prevnar). This new vaccine will add another six serotypes of protection, including 19A that will give us another weapon against the villain microbes.

Major breakthrough!

June 26, 2007

Analysis of:HPV Vaccine Can Reduce Cervical Cancer Cases | www.emaxhealth.com

In our pediatric/adolescent medicine practice, this new vaccine has been extremely well-accepted by parents and teens. There has been very little push-back or concern expressed about using a vaccine to treat an STI. Most parents are eager to have their daughter immunized and protected against these four HPV serotypes.

A potential, significant advance

November 13, 2006

Analysis of:Numax(R) Achieves Primary Endpoint In Preliminary Analysis of Data From Comparative Phase 3 Trial With Synagis(R) | biz.yahoo.com

The efficacy data looks significantly better. Nothing is mentioned about whether administration will be easier than the once a month IM injection Synagis requires. This looks like an evolutionary improvement rather than a revolutionary one.

How to patch the system

November 13, 2006

Analysis of:Skin patches instead of shots? | news.yahoo.com

This has potential, but would be more difficult to incorporate into a system.

No question of inappropriate use

November 13, 2006

Analysis of:Misuse of Home Nebulizers High Among Inner-City Children With Asthma | www.medscape.com

It is reasonable to generalize this study to a broader population. There are problems with prescribing inappropriately, patients using inappropriately, and DME companies inappropriately pushing nebulizers.

How do you get it to work?

November 13, 2006

Analysis of:Pay-for-Performance Plans Now Common Among HMOs | www.nlm.nih.gov

Pay for performance is a great concept. Many practices are unable to provide the data to make it work. Most of the measures chosen are simple, least-common-denominator type efforts and may only have marginal applicability to overall quality of care.

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