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Consolidation of Veterinary Pharmaceutical Companies in Progress

August 13, 2010

Analysis of:Sanofi-aventis to acquire 50% Merck's interest in Merial for US$4 bn | www.pharmabiz.com

Veterinary Pharmaceutical and Biologic Companies have merged from more than 100 to about 10 in the USA over the past few decades.

Rapid DNA Tests to Detect Clostridium difficile needed in Veterinary Medicine

August 10, 2010

Analysis of:Rapid DNA Test to Detect Clostridium difficile Infection Approved by FDA Today | www.medscape.com

Clostridium difficile is a common bacterial intestinal resident in most animals and can serve as a source for transmission to man. Rapid and efficient testing for C. difficile toxins in veterinary medicine would be assistance to infectious disease specialists and public health specialists.

Drug use in animals is important to human health.

July 22, 2009

Analysis of:Animal health offers growth for big pharma | www.reuters.com

Animal health offers growth for big pharma by the production of drugs and pharmaceuticals for treatment and prevention of animal diseases. Also, there is the added benefit and need for clinical and field testing of new products that have demand in treating both animal and human diseases. There are both similar and unique differences in man and animal physiology and pharmakinetics.

Rapid DNA Clostridium difficile test useful for public health laboratories.

July 22, 2009

Analysis of:Rapid DNA Test to Detect Clostridium difficile Infection Approved by FDA Today | www.medscape.com

Clostridium difficile is a bacterium that infects dogs, cats and other animals and is transmissible from animals to man. It is important for veterinary diagnostic laboratories and public health laboratories to monitor infections of C. difficile as preventative measures and control of zoonotic infections.

Evaluation of Influenza Vaccines

May 20, 2009

Analysis of:Novartis receives swine flu virus | newsinfo.inquirer.net

Scientists, medical professionals and the public know that by the time new flu vaccines are produced for use that the specific outbreak is far into the past and the vaccine is no longer in need and is destroyed. Novartis and other vaccine production companies need to dedicate more effort in evaluation of existing and new vaccines.

Roche's real-time PCR for MRSA needs clinical tests

April 9, 2009

Analysis of:New advanced MRSA test in the EU | www.ptemag.com

Roche's LightCycler 2.0 real-time PCR for MRSA will need further validation from designed quality control testing by unbiased clinical diagnostic laboratories.  Provided the new test procedure for MRSA meets the criteria for accuracy, then, clinical tests could prove useful to evaluate the epidemiology of MRSA in various situations. 

Programs to predict mosquito activity important to veterinary medine and one-health.

March 30, 2009

Analysis of:System developed to predict mosquito outbreaks | www.abc.net.au

Arthropod borne diseases are important modes for transmission of pathogenic microbes to man and animal and their interactive environment.  Mosquito's are the vectors for transmission of heartworms in dogs, which is endemic in many states in the U.S., Eastern and Western Equine Encephalitis in birds,horses and man, West Nile viruses and many other significant diseases

Treat African Violets not Bacillus anthracis

February 25, 2009

Analysis of:Clue To Potential New Anthrax Treatment discovered in Houseplant Pest | www.medicalnewstoday.com

Renewed interest in iron binding via siderophores and blocking this component to prevent bacterial infections in man has opened up new revenues for research monies.  However, this approach was not productive nor efficient in past clinical trials and would not appear to be effective in treating respiratory anthrax. 

Judicious use of antimicrobials

February 23, 2009

Analysis of:Irrational Use of Anti microbials | www.indmedica.com

Good judgement and prudence on the part of the medical profession is the key to using antimicrobials to treat infectious diseases.  Education, correct diagnosis, proper use of laboratory medicine, bacterial isolation, antimicrobial susceptibility all need to accompany the use of antimicrobials. 

Antimicrobial resistant bacteria not "superbugs"

October 6, 2008

Analysis of:'Superbugs' That Strike the Sickest Patients | online.wsj.com

Articles with the terms "superbug", "known as gram-negative bacteria" , "so called gram-positve category" and "ultra resistant" do not give the reader much confidence in the "facts and figures" that are presented in the publication.   Hospital microbiology labs, infectious disease specialists, epidemiologist and infection control groups need to design more clinical trials to determine if acquired resistance is truly more significant in nosocomial infections versus environmental bacteria with more innate resistance such as the Pseudomonas sp., Acinetobacter sp., Enterobacter sp., etc. 

Witty approach by Mr. Witty to improve Glaxo's drug pipeline

July 17, 2008

Analysis of:Glaxo Seeks Guidance From Health Systems | online.wsj.com

Asking company investors and pharmaceutical users their opinions about the drugs that are needed seems like a logical approach to the needs for pharmaceutical drug development.  Hopefully, this unique analysis of company policy will be successful and lead to changes that would be successful to other pharmaceutical development companies.  

Experts in the oil industry have stated for the past year that $4 / gal. gas will initiate oil and energy conservation.

May 27, 2008

Analysis of:Producers say $200 oil is possible as prices hit record three days running | www.guardian.co.uk

After the mid '70's, the economists demonstrated a significant conservation of oil and gas for a few brief years.  Smaller more gas efficient cars, 55 mph speed limits, etc.   After the few good or better years of gas prices, this country started back on the "old ways" by making SUV's, Hummers, increased speed limits, etc.    

Expect great benefits from GlaxoSmithKline / AVANT Immunotherapeutics ROTARIX vaccine

May 15, 2008

Analysis of:FDA Approves ROTARIX(R) Rotavirus Vaccine | www.pipelinereview.com

The development and approval of ROTARIX rotavirus vaccine may prove to be one of the best vaccine programs of the early 21st century.  GlaxoSmithKline / AVANT Immunotherapeutics extensive research and clinical trials should be very helpful in getting the use of ROTARIX on a fast tract to providing immunity to the world's newborn children immediately and continuously.          

Clinical Analysis of GSK's Rotarix important to success of vaccine

April 14, 2008

Analysis of:FDA Clears Glaxo Diarrhea - Virus Vaccine | www.nytimes.com

The key to success of marketing Rotarix or similar Rotavirus vaccines is in the design of clinical trials and evaluation of criteria and results of past use of these vaccines in developing countries that have a high incidence of rotavirus diarrhea in infants.  Rotavirus vaccine use is a  prototype for preventive medicine since the key is to provide immunity to an immunologically naive population.

Nycomed's Bradley acquisition could fit expansion into veterinary dermatologics

November 2, 2007

Analysis of:Nycomed signs definitive agreement to acquire Bradley Pharmaceuticals, Inc., strengthening US specialty business | www.pipelinereview.com

Veterinary pharmaceutics have great potential for growth for companies that are willing and able to expand into this market.  This market should be considered by the Nycomed Bradley team as it follows the company philosophy of the Nycomed CEO's "The acquisition enables us to gain critical mass in the dermatology market and provide significant momentum for further add-on investments".  Veterinary dermatological conditions have parallel situations in human dermatology with enough unique causes that create a need for additional pharmaceutics for treatment.  

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