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Cartilage repair/restoration has viable results in well choosen patients

July 25, 2007

Analysis of:Genzyme Announces Positive Results from Carticel® Study at Major Sports Medicine Meeting | www.genzyme.com

Most cartilage repair techniques must take into account the age and biology of the area being treated. We all know that the aging process significantly decreases the healing potential of most collagen based procedures, whether that be skin, tendon, ligament, cartilage or bone. The myriad of techniques including microfracture Autologous OATS, allograft OATS, ACI, syntheic fillers and resurfacing all have their ideal pattients and in most articles, the confounding variables are poorly controlled for. Resultrs will always be better in the healthy, isolated lesion in the non-smokers, younger patient without alignmenet issues. In order to get a cohort of ideal patients, the numbers to independently assess all these technologies would be staggering. The best ideas at this point seem to be the initiaion of the most conservative treatment with progression to more invasive techniques upon determining failure of results with previous procedures.

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