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Current use of Abacavir

August 5, 2008

Analysis of:F.D.A. Urges Genetic Test Before Giving AIDS Drug | www.nytimes.com

we have known about the availability of this test for several months and have been using it even before the FDA recommendations or the recent guideline changes which also recommended it.This addresses to a great extent the issue surrounding HSR (hypersusceptibility reaction) which has kept some clinicians from using abacavir-containing products in the past.The genetic test is not inexpensive and is clearly not 100% accurate. Some public clinics may choose not to use it in order to save funds for other needs (particularly if they serve populations with low incidence of the marker). In my private practice we try to obtain it on most of our patients before they start treatment. Overall, this gives GSK a bit of a push and will encourage some increased use in abacavir.

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