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Over Suppression of Bone Turnover May Be Harmful

July 21, 2008

Analysis of:Drugs to Build Bones May Weaken Them | www.nytimes.com

Bisphosphonates, including medications like Fosamax, prevents normal bone turnover and metabolism. Nephrologists had anticipated similar findings as these recent reports as over-suppression of normal bone turnover may be associated with adynamic bone disease and possibly fractures. The process in kidney disease patients cannot be extrapolated to the normal, non-kidney disease patients directly but these recent findings suggest that similar clinical manifestations may be present in the wider community.

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