Gaurav Shah

Dr. Gaurav Shah MD

Professor of Ophthalmology, WASHINGTON UNIVERSITY MEDICAL CENTER


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Council Member Biography

Gaurav Shah, MD, is Professor of Ophthalmology at the Washington University Medical Center in Missouri. Dr. Shah is a national expert in the care of patients with diabetic retinopathy/diabetic macular edema, age-related macular degeneration, and retinal detachments, as well as the economics of retinal healthcare. He has been involved in the pivotal trials and publications regarding Macugen, Lucentis, and PDT and is working on new combinations of PDT and Avastin. Dr. Shah has presented at many national and international meetings and has published over four book chapters and approximately 100 peer-reviewed articles. He is an elected member of the Retina Society, the Macula Society, and the American Academy of Ophthalmology. Dr. Shah is also involved in 15 phase 2 and phase 3 clinical trials dealing with ARMD and diabetic macular edema, dry macular degeneration, and new drug delivery devices. He is Editor and Chief of the Retina Times (official publication of the ASRS (American Society of Retina Specialists.) (This is me - Update Profile)


Employment History

1999 - Unspecified
Professor of Ophthalmology, WASHINGTON UNIVERSITY MEDICAL CENTER

GLG NewsSM Analyses by Gaurav Shah

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JSM 6427: the new face of armd therapy

July 30, 2007

FDA Accepts Jerini Ophthalmic's IND of JSM 6427 for the Treatment of AMD | www.pipelinereview.com

1.  A molecule that allows on to stop neovascular armd to form from dry armd 2.  A product with a potentially large  market share compared to the current agents available 3.  A compound that could have a sustained drug delivery module

PDT still a viable alternatvie

March 14, 2007

PDT more effective for myopic CNV in patients 55 years and younger, study finds | www.osnsupersite.com

PDT remains a viable option for patients with new blood vessels from high myopia. Despite the era of antivegf therapy PDT may be safer in these patients than repeated injection. This article yet again defies another area for the use of PDT. PDT will be continued to be complemented to the currently available therapies of antivegf for not only myopic degeneration, but also macular degeneration.

Laser to drusen trial

November 20, 2006

Laser Treatment Ineffective In Preventing Vision Loss In Early Age-Related Macular Degeneration | www.pharma-lexicon.com

It is not surprising that laser therapy is not effective for patients with macular degeneration. Initially there was a significant interest in this therapy, but as this well designed trial has shown us that thermal treatment is not the answer for dry ARMD. AREDS I and AREDS II are now the most important vitamin related studies with ARMD. The future for dry ARMD lies potentially with encapsulated compounds that may be delivered to the back of the eye for geographic atrophy. Currently the Anti-VEGF agents Lucentis and Avastin are the gold standard for wet ARMD. PDT in combination with these agents may be useful for decreasing the number in the injections involved.

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