William Shannon

Dr. William Shannon PhD

Founder and President, BioRankings, LLC


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Member of the Healthcare Council

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Council Member Biography

William Shannon, PhD, is an Associate Professor of Biostatistics at Washington University School of Medicine, since 1995; and Founder and President of BioRankings, a pharma IT firm, since January 2007. Dr. Shannon has over 20 years of applied biostatistical expertise in biomedical, pharmaceutical, and biotech research. He has 100 peer-reviewed publications in areas such as oncology, genetics, cardiology, pulmonology infectious disease, sleep medicine, health care delivery, statistics, and other areas. By making complex biostatistical ideas understandable, Dr. Shannon can help companies gain insight on the strengths and weaknesses of pre-clinical data and clinical trials that may impact a company's long term viability, and understanding of statistical data to protect investment. (This is me - Update Profile)


Employment History

2007 - Unspecified
Founder and President, BioRankings, LLC
1995 - Unspecified
Associate Professor (Tenured), THE WASHINGTON UNIVERSITY

GLG NewsSM Analyses by William Shannon

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The data and news behind the FDA decison

January 31, 2010

FDA to Re-evaluate Use of Erythropoiesis-Stimulating Agents in Chronic Kidney Disease | www.parenteaubc.com

The FDA announced plans for an advisory review board in 2010 to re-evaluate erythropoiesis-stimulating agents (ESAs) usage and dosing for the treatment of anemia in chronic kidney disease. This decision followed publication of a report indicating ESAs provide no benefit in outcome compared to placebo, and increases stroke rates.

Cancer Immunotherapy Explained

January 31, 2010

Immunotherapy Demystified: Investing In High Risk, High Reward Opportunities In Cancer Therapeutics | www.parenteaubc.com

The Parenteau BioConsultants and BioRankings Alliance, both GLG consultants, have released a free ebook for investors and biotech executives -- "Immunotherapy Demystified: Investing In High Risk, High Reward Opportunities In Cancer Therapeutics".This ebook presents the necessary background of the biology and statistics of this field to help the investor avoid the hype and spin behind cancer immunotherapies, and reduce the risk of their investment decisions. 

Meta-analysis of probiotics in atopic dermatitis

April 16, 2009

Probiotics for the treatment or prevention of atopic dermatitis: a review of the evidence from randomized controlled trials. | www.ncbi.nlm.nih.gov

The use of meta-analysis to evaluate probiotics in this condition is commendable.  The abstract suggests that improvement may be real, but the evidence presented indicates that probiotics may be ineffective on careful reading.  The abstract is lacking information needed to determine the quality of the meta-analysis and whether its results/suggestions should be considered in investment decisions.

New FDA effort takes aim at genomics: Inherent risk to investors

February 6, 2009

New FDA Effort to Take Aim at Genomics | www.genomeweb.com

The risk to an investor in genomic or personalized medicine is significant and a clear understanding of the low power and high risk of false-positives needs to be kept in mind.  The establishment at the FDA of a senior scientist to oversee and coordinate genomic activities is necessary but not necessarily sufficient to insure that future genomic treatments are effective. 

Eli Lilly's Personal Medicine Goal

November 27, 2008

Personal medicine is goal of Eli Lilly & Co. | www.azcentral.com

The Chairman of Eli Lilly announcing that personalized medicine (e.g., pharmacogenetics) is a major shift in strategy for big pharma could impact in a significant way the market share for new drugs and the amount of money for research needed to bring a targeted therapy to market. If this strategy is widely accepted the likely impact on small biotech firms will be a significant increase in their value and more acquisitions.

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GLG Study Groups with William Shannon(?)

Study Group Name No. Members
Biostatisticians 358
Biostatisticians (US) 254

GLG Live Meetings with William Shannon(?)

William Shannon has not participated in any GLG Live Meetings.

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