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David RosenbergChief of Psychiatry and PsychologyCHILDREN'S HOSPITAL OF MICHIGAN What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

Plans focusing on Wellness all too often forget mental health

April 30, 2007

Employers' plans emphasize wellness | www.pennlive.com

Mental health problems are associated with more physical problems

Mental health problems such as depression associated with more occupational problems, days off, etc             

David RosenbergChief of Psychiatry and PsychologyCHILDREN'S HOSPITAL OF MICHIGAN What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

Proper Pharmacologic Treatment of ADHD reduces risk of substance abuse

April 30, 2007

A New Look at the Relationship and Management of ADHD and Comorbid Substance Use Disorder | cmsprepub.medscape.com

  Treating ADHD reduces risk of comorbid substance abuse with appropriate doses of medication

Untreated ADHD and substance abuse increases risk for dependence, adverse outcome including jail, sociopathy, adverse impact on occupational, social and personal functioning 

David RosenbergChief of Psychiatry and PsychologyCHILDREN'S HOSPITAL OF MICHIGAN What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

More Generics Needed

April 30, 2007

Caraco Pharmaceutical Laboratories Ltd. Announces FDA Approval To Market Generic Ambien(R) | www.medicalnewstoday.com

Urgent need for generic

Proprietary medications often prohibitively expensive

Insurance plans often prefer generic equivalents

David RosenbergChief of Psychiatry and PsychologyCHILDREN'S HOSPITAL OF MICHIGAN What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

Urgent Need for Better Treatement for Excessive Sleepiness

April 30, 2007

Vanda Pharmaceuticals Initiates Phase II Clinical Trial for VSF-173 in Excessive Sleepiness | www.pipelinereview.com

  Urgent need for treatment for excessive sleepiness

Affects millions of Americans

One of most common presenting problems to primary care, psychiatry and neurology clinics where symptom may be primary or part of other primary condition

David RosenbergChief of Psychiatry and PsychologyCHILDREN'S HOSPITAL OF MICHIGAN What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

Restless Leg Syndrome Commonly Presents to Psychiatry Clinics

April 30, 2007

XenoPort Reports Positive Top-Line Phase 3 Trial Results of XP13512 in Restless Legs Syndrome | www.pipelinereview.com

This has huge significance as restless leg syndrome not only presents to primary care physicians and neurologists but frequently to psychiatrists

Presentation often related to sleep disturbance

Presentation of movement abnormalities/distress

David RosenbergChief of Psychiatry and PsychologyCHILDREN'S HOSPITAL OF MICHIGAN What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

Cortisol and Psychiatric Disorders

April 30, 2007

Scientists unravel clue in cortisol production | www.rxpgnews.com

Depression is associated with abnormalities in cortisol production, in the hypothalamic-pituitary-adrenal axis and related brain imaging abnormalities

Anxiety disorders area associated with abnormalities in cortisol production

Eating disorders are associated with abnormaliteis in cortisol production

David RosenbergChief of Psychiatry and PsychologyCHILDREN'S HOSPITAL OF MICHIGAN What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

More of the Same

April 2, 2007

What's new in the antidepressant market when generics rule the roost? | atlanta-institute.com

1. Currently, generic antidepressants are better and cheapter option than proprietary medications
2. The way to go is targeting novel systems, e.g, glutamate, rather than same systems

David RosenbergChief of Psychiatry and PsychologyCHILDREN'S HOSPITAL OF MICHIGAN What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

When Prescribed Appropriately Sleep Medications Can be Very Safe and Effective

April 2, 2007

Ranbaxy Receives Tentative FDA Approval to Manufacture and Market Zolpidem Tablets | pharmalive.com

1. Generic sleep medications (as for any medication) have considerable advantage in terms of cost
2. When prescribed correctly, sleep medications (as for any medication) can be quite effective with few side effects.
3. These can be dangerous when not taken correctly and when appropriate personal and family psychiatric history not taken.

David RosenbergChief of Psychiatry and PsychologyCHILDREN'S HOSPITAL OF MICHIGAN What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

Timing is Everything

April 2, 2007

Kickboxing 'causes brain damage' | news.bbc.co.uk

1. Brain continues to develop throughout adolescence and young adulthood.
2. More brain plasticity earlier rather than later.
3. Brain development throughout adolescence and into young adulthood. Time for more things to go wrong, altered development, also possible for more to be 'corrected'

 

David RosenbergChief of Psychiatry and PsychologyCHILDREN'S HOSPITAL OF MICHIGAN What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

FDA Approval For Medication is Important

March 30, 2007

FDA Approves Duloxetine for Anxiety | journals.elsevierhealth.com

1. FDA Approval for new condition, e.g, anxiety, especially important to primary care practioners and increasing their comfort zone.
2. FDA approval for newer condition somewhat less important for specialists, e.g, psychiatrists who may be using for other conditions already

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