GLG News by Volume Trend Experts on Pacemakers (US)

Daniel Weiss, President

Daniel WeissPresidentWeiss Consulting Groups, Inc. What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

Medtronic - the new Guidant?

October 18, 2007

Medtronic Pulls Heart Device Wires | www.thestreet.com

The current recall is yet another in the world of cardiac rhythm devices. The ICD market is already shakey and may be adversely affected. Will Medtronic's reputation suffer?

Daniel Weiss, President

Daniel WeissPresidentWeiss Consulting Groups, Inc. What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

TB-402 - the type of anticoagulant patients and physicians are looking for as a warfarin replacement

September 17, 2007

ThromboGenics and BioInvent Announce Successful Completion of Phase I Clinical Trial of the Anticoagulant TB-402 | www.pipelinereview.com

TB-402 is a new anticoagulant candidate that seeks to fill a desperate unmet need in a variety of different medical conditions. It would be easily administered with a low risk of patient noncompliance, have reversible effects, and potentially safer than currently available alternatives.

Louis RoccoSystem Director of Purchasing HALLMARK HEALTH SYSTEM, INC. What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

Comments

July 2, 2007

Mail order drugs flying off shelves | www.gazette.com

I could not agree more that people should have a choice and maybe the pricing markey is the US will finally drop after how it see it will work all pharmacies across the country. The manufacturers need to be held responsible for this issue, they caused it with raising prices and making more of a profit. They should join in with the oil industry these two make a good pair on how to rep off the consumer.

Keith Allen, Director, Cardiothoracic Vascular Surgery Research

Keith AllenDirector, Cardiothoracic Vascular Surgery ResearchMid America Heart & Lung Surgeons, PC What is a GLG Leader?|The Gerson Lehrman Group&reg; (GLG) Leader Program<sup>SM</sup> is our premium Member Program<sup>SM</sup>. Those identified as GLG Leaders are in the top 5% of GLG CouncilRank and have an exclusivity agreement with GLG.

Drug Eluting Stents:The Next Vioxx

December 14, 2006

Trading restenosis for Thrombosis? New questions about drug-eluding stents. | content.nejm.org

1. DES whether used on or off label will likely require life long anticoagulation with Plavix like drugs.

2. The incidence of late thrombosis is significant when anticoagulation is interrupted for events such as elective surgery.

3. Unlike restenosis following insertion of a bare metal stent which rarely results in death to the patient, late thrombosis following use of a DES results in a 50% mortality.

4.  Hints of this problem were present during FDA presentations prior to DES approval which may lead to significant liability as this problem becomes more apparent.

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